Eat well. Anticoagulant Food-Drug Interactions. These include deep vein thrombosis, factor V Leiden, myocardial infarction, and polycythemia vera, among many others. Get useful, helpful and relevant health + wellness information. The opinions expressed here are the views of the writer and do not necessarily reflect the views and opinions of News Medical. Its the most common blood clotting disorder thats inherited, or passed down within biological families. Since then I was also diagnosed w My name is MARTIN R. LEMIEUX, and for over 20 years now Ive survived five DVTS BLOOD CLOTS in my left leg, one clot in my right leg, and another clot in my left pelvic area. It does not increase the risk of myocardial infarction (heart attacks) or arterial strokes. But the plan would have to be modified to make it appropriate if you have these or other conditions. 0000001440 00000 n "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. What websites do you recommend? Did I get the mutation from both parents or just one? 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Its important to go to all of your appointments and talk to your provider about any questions or concerns you have. Check with your provider. The two most common hereditary thrombophilia conditions are the factor V Leiden and prothrombin 20210 gene mutations, both of which have been the subject of previous Cardiology Patient Pages. AskMayoExpert. Most people who have this disorder never develop blood clots or have pregnancy complications. Fewer than 1 in 100 people of Asian descent. This is known as deep vein thrombosis (DVT), which most commonly occurs in the legs. Accessed June 4, 2018. Factor V Leiden (FAK-tur five LIDE-n) is a mutation of one of the clotting factors in the blood. Pruthi RK (expert opinion). Counseling prior to taking birth control pills or before becoming pregnant. When you are injured, your body stops bleeding by changing liquid blood into a plug (clot) that blocks the leaks in damaged blood vessels. 0000000016 00000 n 0000001362 00000 n Want to talk about Multiple Myeloma: Anyone else? Anticoagulants are commonly used in the treatment of diseases in which there is an increased risk of blood clot formation. If youve had a deep vein thrombosis or pulmonary embolism before and know you have the prothrombin gene mutation, you may need a prescription for low-dose (preventive doses) of an injectable blood thinner (such as heparin or a low-molecular-weight heparin) during your pregnancy and for a few weeks after delivery. The weight loss and increased activity that The 5-Factor Diet promises are key to the prevention and treatment of many conditions, including heart disease, high blood pressure, and diabetes. Does It Allow for Dietary Restrictions or Preferences? 76 0 obj<> endobj Follow Canadas Physical Activity Guide. What are the chances of passing down the genetic mutation to my children? Coming to a Cleveland Clinic location?Hillcrest Cancer Center check-in changesCole Eye entrance closingVisitation, mask requirements and COVID-19 information, Notice of Intelligent Business Solutions data eventLearn more. 9500 Euclid Avenue, Cleveland, Ohio 44195 |, Important Updates + Notice of Vendor Data Event, (https://pubmed.ncbi.nlm.nih.gov/31577252/), (https://www.stoptheclot.org/factor-v-leiden/). WebMD does not provide medical advice, diagnosis or treatment. Nelson JG. Harvard T.H. Mayo Clinic does not endorse companies or products. Rather, it's key to keep your intake of the nutrient consistent. (https://www.heart.org/en/health-topics/venous-thromboembolism/prevention-and-treatment-of-excessive-blood-clotting-hypercoagulation), (https://www.redcrossblood.org/donate-blood/how-to-donate/eligibility-requirements/eligibility-criteria-alphabetical.html), Visitation, mask requirements and COVID-19 information, Heart, Vascular & Thoracic Institute (Miller Family). Enjoy a variety of foods from the 4 food groups. The 5-Factor Diet is a bundled diet and exercise plan that may help you lose weight and become more active. You may have a higher risk of getting: Pulmonary embolism. The liver is responsible for breaking down alcohol and some medications, and this may cause a slower than normal metabolism of the anticoagulant, increasing the drug concentration in the blood, and hence the risk of bleeding. Do you know someone who has suffered a deep vein thrombosis, pulmonary embolism, or other type of venous blood clot? If you cant walk around, flex your ankles and point your toes up and down. About 1 of every 250 Black people in America has the prothrombin gene mutation. Having Factor V Leiden does not appear to increase the chances of developing a heart attack or stroke. Or ask someone to drive you to the nearest emergency room. Advertising revenue supports our not-for-profit mission. 0000003553 00000 n Toll Free: 877.4.NO CLOT, National Blood Clot Alliance In a healthy individual who is bleeding, platelets and clotting factors or specific proteins form a clot to stop the bleeding. U.S. National Institutes of Health, National Library of Medicine. Mayo Clinic does not endorse companies or products. News-Medical, viewed 04 March 2023, https://www.news-medical.net/health/Anticoagulant-Food-Drug-Interactions.aspx. Policy. Here's what foods they have in common, and how to build a healthy diet when you have factor V Leiden: 1. This content does not have an English version. There is also a 50% chance that your child will inherit your normal Factor V gene. These blood clots can be life-threatening. Advertising on our site helps support our mission. Factor V Leiden is the most common one. DVT or a PE soon after starting birth control pills or hormone therapy. In this article, News-Medical talks to Sartorius about biosensing and bioprocessing in gene therapy, National Heart, Lung, and Blood Institute. But if you do, prompt treatment can manage your condition. Tips on transitioning to a whole food fertility diet. RTs endorsements. Talk to your provider to see if you should be taking a blood thinner. This mutation can increase your chance of developing abnormal blood clots, most commonly in your legs or lungs. advice, care, or treatment. Why Am I Still Anemic After Taking Iron Supplements? Where's the Health Benefit? Is this an emergency? Advertising on our site helps support our mission. People with Factor V Leiden make an altered factor V protein as a result of a mutated gene. Factor V Leiden (pronounced FAK-ter five LYE-den) is a blood clotting disorder that raises your risk of abnormal blood clots. Vitamin K is necessary for making the proteins that aid in blood clotting, according to the Harvard T.H. AHA: "Shaking the Salt Habit to Lower High Blood Pressure", Harvard T. H. Chan School of Public Health: "Vitamin K", AHA: "Understanding Your Risk for Excessive Blood Clotting", Using hormone therapy, including birth control pills, Immobility, either from lack of exercise, disability or sitting for long periods of time. US Pharm. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education. https://www.uptodate.com/contents/search. Inheriting two copies one from each parent significantly increases your risk of developing blood clots. Although the prothrombin gene mutation is the second most common inherited predisposition to a deep vein thrombosis or pulmonary embolism, it is the weakest of all inherited clotting disorders in terms of risk of causing abnormal blood clots. Your provider may think you have a clotting problem if you: There is no specific treatment for the mutation itself. Doctors generally prescribe blood-thinning medications to treat people who develop abnormal blood clots. How does prothrombin gene mutation affect my body? In most people, a protein called activated protein C regulates the activity of . If you have factor V Leiden and have developed blood clots, anticoagulant medications can lessen your risk of developing additional blood clots and help you avoid potentially serious complications. In this interview, we speak to Ceri Wiggins, a Director at AstraZeneca, about the many applications of CRISPR and its role in discovering new COPD therapies. However, interactions with food, drinks, herbs, and other medications may still occur. You may be treated with blood thinners until the risk has passed. AskMayoExpert. Exercise regularly for good circulation in the veins of your legs. If you have factor V Leiden, you may have many questions. NBCA provides the information and materials on this site for general information purposes only. A single copy of these materials may be reprinted for noncommercial personal use only. These conditions can be life-threatening and require immediate medical treatment. The prothrombin gene mutation can make you more likely to get harmful blood clots, but you may never get one. You may not need to do anything other than lead a healthy lifestyle to minimize the risk of a deep vein thrombosis or pulmonary embolism. This is caused by a change (mutation) in the gene for this protein. The normal blood clotting process goes to work right away when you get a cut platelets rush to the site to seal it, and a substance called fibrin aided by factor V helps the platelets to form a clot. Diseasemaps 2023, FACTORV LEIDEN AND LIVEDOID VASCULOPATHY SURVIVOR. Foods to limit when you're following a heart-healthy diet include: 1. What about my children?. With Factor V Leiden the risk of a blood clot increases with age 0 100 200 300 400 500 600 700 800 900 1000 Risk per 100,000 people Childhood 20's 40's 80's Having 1 Factor V Leiden gene (heterozygous type) slightly increases the chance of developing a blood clot. The mutation in itself is not a reason to avoid donating blood, but you should not give blood if you are using an anticoagulant (blood thinner). Middeldorp S, Coppens M. Hereditary Thrombophilia. Large amounts of garlic, ginger, glucosamine (an amino sugar), ginseng, and ginkgo should be avoided while on anticoagulant medications as they may increase the risk of bleeding. Your child will have either the heterozygous or homozygous type, depending on whether the gene passed down from his or her other parent is normal (Factor V) or abnormal (Factor V Leiden). And it provides simple recipes that promise no more than 5 ingredients and 5 minutes of prep time. Factor V Leiden doesnt affect life expectancy in most people. Inherited thrombophilias in pregnancy. This caution also extends to drug-food interactions. Blood clots can cause serious problems in your body when they block blood flow, keeping oxygen from getting to your cells. Dont buy ones from the store or wear them without talking to your provider first. We use cookies to enhance your experience. Research is mixed concerning the weight loss advantage of eating smaller meals more often, but this may have other health benefits. But you should talk to your provider about what you can expect in your individual situation. You have 1 Factor V Leiden gene from one parent and 1 normal Factor V gene from your other parent. If you have factor V Leiden, you inherited either one copy or, rarely, two copies of the defective gene. with these terms and conditions. In your body, you have 100% of Factor V Leiden and no normal Factor V. This happens in less than 1 out of 100 people. As such, daily intake or extra supplementation with vitamin K is typically unnecessary to keep body stores at healthy levels. A cough that produces bloody or blood-streaked sputum. Factor V Leiden is an inherited disorder. New York, N.Y.: McGraw-Hill Education; 2016. https://accessmedicine.mhmedical.com. Accessed June 4, 2018. Fortunately, about 95 percent of people with this condition never develop a clot, according to the National Institutes of Health. Cost: Just your groceries. There are many programs, websites and tools that can help you quit. Keywords: papillophlebitis, factor v leiden, methylenetetrahydrofolate reductase mutation, retinal venous disease Introduction Papillophlebitis is a rare disease (higher prevalence in women of 20-35 years old), characterized by optic disc edema, retinal venous engorgement, and retinal hemorrhages, mainly located within the peripapillary area . Connect with others like you for support and answers to your questions in the Blood Cancers & Disorders support group on Mayo Clinic Connect, a patient community. Pasternak, H. The 5-Factor Diet, Ballantine Books, 2009. diabetes.org: "Glycemic Index and Diabetes. Deficiencies of antithrombin and proteins C/S, elevated fibrinogen levels, and other clotting disorders also raise risk. Your brothers and sisters may have inherited the mutated gene for Factor V Leiden, just like you did. How frequently do I need to have checkups. Most people with factor V Leiden never develop abnormal clots. "Anticoagulant Food-Drug Interactions". Each 5-Factor five-ingredient meal must include all five must-have food groups: The 5-Factor Diet doesnt mention alcohol specifically, but on the diets cheat day you may eat or drink anything you like. Each 5-Factor five-ingredient meal must include all five must-have food groups: Protein (egg whites, fish, lean meats/poultry, fat-free dairy) Complex carbohydrates (vegetables, sweet potato,. You must do the 25-minute 5-Factor workout five days a week. you have a medical emergency, call 911 immediately. Zoppi, Lois. These medications (called anticoagulants) help to prevent clotting. Fruits and vegetables: Get at least five servings of fruits and veggies throughout the day, and incorporate all different kinds. Adults need approximately 1 microgram/kg body weight of vitamin K a day. Fruits and vegetables: Get at least five servings of fruits and veggies throughout the day, and incorporate all different kinds. Coming to a Cleveland Clinic location?Hillcrest Cancer Center check-in changesCole Eye entrance closingVisitation, mask requirements and COVID-19 information, Notice of Intelligent Business Solutions data eventLearn more. Drink plenty of fluids (without alcohol). Factor V Leiden This results from a genetic change that increases the risk of blood clots, especially in deep veins. A genetic mutation (change) causes factor V Leiden. If your factor V Leiden requires you to take anticoagulant medication, here are some steps that might help you prevent injury and avoid excessive bleeding: Avoid playing contact sports or engaging in other activities that could result in physical injury. What's more, they can help lower blood pressure. News-Medical. In fact, the vast majority (9 out of 10) never develop abnormal blood clots. National Heart, Lung, and Blood Institute. 0000008077 00000 n Just by eliminating junk food, simple carbs, and high-calorie drinks, as in the 5-Factor Diet, most people are likely to see a dip on the scale. If youve been diagnosed with DVT or a PE, youll have frequent follow-up appointments so your provider can check treatment progress. (https://www.stoptheclot.org/learn_more/prothrombin-g20210a-factor-ii-mutation-links/), (https://www.merckmanuals.com/home/blood-disorders/excessive-clotting/excessive-clotting?query=prothrombin%20gene%20mutation). Thank you to @angiodynamics one of our corporate sponsors for the 100,000 Reasons Challenge for their support during #BCAM2023. (On the contrary, these are all heart-healthy foods.). This site complies with the HONcode standard for trustworthy health information: verify here. Last reviewed by a Cleveland Clinic medical professional on 10/04/2022. If you or a loved one have factor V Leiden, you might feel scared about what the future will bring. Last reviewed by a Cleveland Clinic medical professional on 09/28/2021. Anticoagulants, commonly called blood thinners, are a group of medications that impede the blood clotting process. Women have a greater chance of developing a blood clot during pregnancy. This mutation can increase your chance of developing abnormal blood clots, most commonly in your legs or lungs. Exercise: Required. This content does not have an English version. Though exercise is an important part of the 5-Factor Diet, the recommended amount falls a bit short of the 150 minutes a week of aerobic activity coupled with strength training that most experts recommend. During long car rides, stop every few hours and take a short walk. Talk with your doctor about the risks and benefits of taking these medications. Alcohol interacts with a large number of medications. The factor V Leiden mutation does not itself cause any symptoms. Clots can form in the veins near your bones that carry a lot of blood (deep veins), a condition called deep vein thrombosis. It is not a disease. What are my risks? Vitamin K is found in the following foods: Flaxseed may inhibit the proper absorption of anticoagulants. Because its an inherited condition, you cant prevent the prothrombin gene mutation. Avoid smoking, vaping and tobacco use. A lot of people carry the genetic mutation and a few people develop blood clots that are related to Factor V Leiden. Factor V Leiden is the most common inherited condition causing increased blood clotting. Limited sodium: Get less than 2,300 mg of sodium daily, per the American Heart Association. Try to build up to 150 minutes of moderate-intensity. Having 2 Factor V Leiden genes (homozygous type) makes the risk much greater . 0 If you have symptoms of a pulmonary embolism, you should go to the closest emergency room. The American Heart Association cites the following as risk factors for blood clots: 5 Symptoms of a Blood Clot You Should Know. Stand up and walk around during long flights. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Your skin may also feel warm to the touch or look red or discolored. Individuals who happen to know that they have factor V Leiden but have never had blood clots dont have to be prescribed any blood thinners. Your doctor may suspect factor V Leiden if you've had one or more episodes of abnormal blood clotting or if you have a strong family history of abnormal blood clots. Here's some information to help you prepare for your appointment. a V@ C= 0000236831 00000 n Factor V Leiden may lead to deep vein thrombosis or a pulmonary embolism, which are serious medical emergencies. Policy. Bauer KA. 0000002423 00000 n This can be a life-threatening situation. .wpcdt-timer-24806 {background-color: #aaaaaa;}.wpcdt-timer-24806 .wpcdt-title, .wpcdt-timer-24806 .wpcdt-desc, .wpcdt-timer-24806 .wpcdt-desc p{color: #b81d32;}.wpcdt-timer-24806 .wpcdt-clock-circle h4, The disorder is most common in people who are white and of European descent. Direct oral anticoagulants (DOACs) are expected to replace VKAs because of their increased safety margin. Accessed June 4, 2018. One of these factors is Factor V (FV) Leiden (rs6025), which is a missense variant caused by a single nucleotide polymorphism (SNP) in the F5 gene. Barbara Woodward Lips Patient Education Center. Get useful, helpful and relevant health + wellness information. 2. Factor V Leiden Information for Patients and Families Factor V Leiden is a blood clotting disorder. Avoid foods high in vitamin k (leafy greens mostly), certain supplements, and avoid consuming too much alcohol. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. In: Williams Hematology. A DVT may not cause any symptoms. 3. startxref Before using birth control pills or hormone therapy for menopause. 5. 0000006951 00000 n A. Its important to talk to your provider about any concerns you have related to life expectancy or future complications. It is important to discuss potential interactions between existing and new medications to prevent or recognize any side effects. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Smoking Pot Every Day Linked to Heart Risks, Artificial Sweetener Linked to Heart Risks, FDA Authorizes First At-Home Test for COVID and Flu, New Book: Take Control of Your Heart Disease Risk, MINOCA: The Heart Attack You Didnt See Coming, Health News and Information, Delivered to Your Inbox. In your body, you have 50% Factor V Leiden and 50% normal Factor V. This happens in about 5 out of 100 people of Caucasian decent. Heterozygous Factor V Leiden If you inherited one Factor V Leiden gene from one parent, you have the heterozygous type of Factor V Leiden. For children with one affected gene, the chance of getting a blood clot increases 10 times. However, it is often advised to avoid foods high in Vitamin K. Below is a list of foods that should be avoided because of their . Compilation of the top interviews, articles, and news in the last year. Some research shows that factor V Leiden impacts pregnancy. If you get the mutation from one of your parents, you are heterozygous (you have only one abnormal copy of the Factor II gene, but the gene from your other parent is normal). If youcannot reach your doctor, go to the nearest hospital emergency room. Talk to your healthcare provider to receive advice tailored to your needs. If you have this disorder, you may experience: Factor V Leiden doesnt raise your risk of heart attacks, strokes or blood clots in the arteries of your legs. 4. Youll have the prothrombin gene mutation for life, since its part of your genetic makeup. %%EOF In rare cases, you may need a catheter procedure or surgery to remove the bulk of the clots. Genetic and Rare Disease Information Center. If your provider feels its warranted, theyll order blood tests, including: Simply having a family history of blood clots may not be reason enough to run these tests. Read below where Experts have answered questions about Factor V Leiden. I was placed on maternity leave and put on bed rest. Cleveland Clinic is a non-profit academic medical center. 9th ed. When you are ready, talk with your health care provider for advice and help to lose weight. This helps keep the blood flowing in your legs. But your provider can help you keep your blood from clotting too much. Keeping your intake of vitamin K at a even level will help maintain your blood thinners (especially warfarin) levels. 9th ed. Some issues that can be discussed with your doctor include: Other than the increased risk of developing DVT or PE, factor V Leiden may increase the risk of miscarriage or other pregnancy complications, such as preeclampsia and eclampsia, placental abruption (when the placenta separates too early from the wall of your uterus), and having a fetus that grows slower than is usual. No foods can change your genetics, but having the right type of diet may prevent your condition from getting worse. There are no pre-made foods or supplements to buy. Keep going to your follow-up appointments with your provider, especially if youre taking a blood thinner. Other things can add to your blood clot risk, including: Youll need a specific blood test to check for the prothrombin gene mutation. Together we can #stoptheclot! If you do, another blood test that examines your genes (called DNA) will be done to find out if Factor V Leiden is the cause of the resistance and what type of Factor V Leiden you have. https://www.uptodate.com/contents/search. A family history of factor V Leiden increases your risk of inheriting the disorder. Going on a long flight or a very long road trip. This field is for validation purposes and should be left unchanged. However, the disorder raises your risk compared to people without the disorder. Everyone is born with two copies of the factor V pronounced factor five gene. Do I need to limit my activity in any way? This change causes it to resist other proteins that stop excessive clotting. If you have the heterozygous type, there is a 50% chance that your child will inherit a Factor V Leiden gene from you. 2. It even tells you what staples to keep on hand so you will always be able to get a quick meal together. The nutrient can interact with blood-thinning meds, but the idea is not to avoid foods high in vitamin K, like broccoli, kale, spinach and collard greens. They are prescribed to avoid the development of harmful blood clots. Start With This 7-Day Meal Plan, 10 Effortless Ways to Finally Cut Down on Salt. About 1 of every 250 Black people in America has the prothrombin gene mutation. Still, there is research that suggests that a diet of low GI foods is more likely to cause weight loss, at least in the short term. The mutation does not cause any symptoms in and of itself. Should people with Factor V Leiden avoid Vitamin K? Most people with this disorder never develop a blood clot. What types of side effects can I expect from the medication? Factor V Leiden resists the effects of Activated Protein C, so it takes longer to turn off Factor V Leiden. Build physical activity into your daily life. As a result, factor V works in overdrive, making your blood more likely to clot when it shouldnt. 9500 Euclid Avenue, Cleveland, Ohio 44195 |, Important Updates + Notice of Vendor Data Event, (https://medlineplus.gov/genetics/condition/prothrombin-thrombophilia/#resources). As a result, your blood may clot more easily than it should, leading to serious complications. Mayo Clinic, Rochester, Minn. June 17, 2018. It increases the chances that your blood will form abnormal blood clots that can be dangerous. Wear compression stockings if your provider prescribes them for you. According to NutritionData, the best sources of folate per 100 g serving are: Beans and lentils (~50% RDI) Raw spinach (49% RDI) Asparagus (37% RDI) Romaine (Cos) lettuce (34% RDI) Broccoli (27% RDI) Avocado (20% RDI) Oranges/Mangoes (~10% RDI) The Top 5 Worst Foods for Your Heart, According to a Dietitian. Instead, they have an different form called Factor V Leiden. Your doctor can confirm that you have factor V Leiden with a blood test. In: Tintinalli JE, Ma O, Yealy DM, Meckler GD, Stapczynski J, Cline DM, Thomas SH, eds. Anticoagulant Food-Drug Interactions. Maybe youve already had to deal with a blood clot and wonder if youll face another. https://www.uptodate.com/contents/search. professional diagnosis, opinion, treatment, or services to you or any individual. Most people have never heard of Factor V Leiden. This disorder may raise your risk of a miscarriage or other complications. Most people with factor V Leiden never develop abnormal clots. Up to 1 in 50 people who are Black, Hispanic or Native American. If you have Factor V Leiden, you have a greater chance of developing blood clots. Whole grains: Choose whole grains like whole-grain bread, quinoa, farro and brown rice rather than refined grains, such as white bread, white rice, crackers and baked goods made with white flour. We inherit one gene from our mother and one from our father. https://rarediseases.info.nih.gov/diseases/6403/factor-v-leiden-thrombophilia. All rights reserved. Here's what foods they have in common, and how to build a healthy diet when you have factor V Leiden: Advertisement 1. Or maybe youve had no issues, but your loved one needed treatment for DVT. Farshchi, H. American Journal of Clinical Nutrition, January 2005. Though scientific research on The 5-Factor Diet is lacking, the plan uses sound nutrition principles of healthy eating and weight loss. Accessed June 4, 2018. Will Eating More Protein Help Your Body Gain Muscle Faster? Vitamin K is a necessary element in the blood clotting process. .wpcdt-timer-24806 .wpcdt-clock .wpcdt-digits, The majority of people born with this mutation will not develop an abnormal blood clot in their lifetime. On a long flight, take regular walks down the aisles of the plane. If you smoke, consider the benefits of quitting. (https://pubmed.ncbi.nlm.nih.gov/34540419/), (https://www.genome.gov/Genetic-Disorders/Factor-V-Leiden-Thrombophilia), (https://medlineplus.gov/lab-tests/coagulation-factor-tests/), (https://medlineplus.gov/genetics/gene/f5/), Visitation, mask requirements and COVID-19 information, Heart, Vascular & Thoracic Institute (Miller Family). %PDF-1.5 % If you have an inactive (sedentary) lifestyle, consider how you could gradually increase your physical activity at home, school, work or play. Accessed June 4, 2018. If you have factor V Leiden, there are other ways you can help reduce your risk of developing a blood clot beyond your diet. Limitations: You can eat anything you want on your weekly cheat day." Its important to learn the symptoms so you can seek immediate medical care. One or both of the factor V genes can be mutated and cause the altered form of the factor V protein known as the Factor V Leiden protein to be made. Mayo Clinic, Rochester, Minn. June 17, 2018. Factor V Leiden (FAK-tur five LIDE-n) is a mutation of one of the clotting factors in the blood. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2017.
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